How about a trip to Harvard? Call for Speakers for National Centers for System Biology (NCSB) Annual Conference, June 14-16, 2016

We are completing the speaker’s list for SBHD 2016 and have held spaces for all 14 of NCSB Centers including CRSB – but we will start to fill these spots with other speakers if we do not hear from you by December 11, 2015.

CRSB will provide reimbursement for all registration, travel, hotel, and food.*

If you would like to attend the 2016 meeting, we need to hear from you right now. You will recall that that NCSB meetings themselves have been discontinued but we are combining the 2016 NCSB PI meeting with The International Conference on Systems Biology of Human Disease (SBHD; see Sarah Dunsmore’s email below). SBHD is jointly sponsored by the Harvard Program in Therapeutic Science and the BioQuant Program at the University of Heidelberg and will be held at the Broad Institute in Cambridge, MA from June 14-16, 2016.
SBHD has been held annually for nearly a decade and alternates between Boston, MA and Heidelberg, Germany. The conference takes a broad perspective on the application of systems and systematic biology to human disease and typically attracts several hundred participants from industry and academe. Repeat attendance has created a dedicated and committed SBHD community enlivened by a substantial number of new participants, ensuring an engaged and knowledgeable audience.

Note that NCSB will be responsible for their own travel and lodging expenses – as usual for our annual meetings. Registration fees for all participants in the joint meeting will be the same as those for regular SBHD attendees (TBD) although we offer a limited number of scholarships to cover the registration fees for those who are unable to pay (e.g. undergraduates) and the application details for those will be announced on the SBHD 2016 website when it is up and running.

If you are interested in attending please let Brigid know at 

See how Cas9 proteins search for DNA for gene editing (Video)

For more information see the Innovative Genomics Initiative's Website

All Hands Collaborating! CRSB December Quarterly Meeting: December 18th, 2015

We have a great line up for our upcoming CRSB December Quarterly meeting, December 18th, 2015 – 8:30-12:30 with lite breakfast fare, coffee, and lunch provided (in exchange for your completed Collaboration survey.*)

Our speakers include:  Guest Speakers – Hiten Madhani, UCSF, and UC’s own Michael Rape, as well as CRSB Project speakers, esteemed Yeon Lee from Donald Rio’s Lab, and James Peter Lloyd from Steven Brenner’s Lab.  During the last hour, our leadership faculty team will break off into a separate grant writing and planning discussion to continue the work past current NIGMS P50 funding.  

During our regular morning meeting, the larger membership will also spend time talking about how each of us collaborates across labs, project and cores, to fill in some blanks from a leadership survey last April.

What kinds of collaboration have you been involved in?

Who have you worked with outside of your regular lab efforts?  Talked to?  Consulted with?  Have you shared reagents? equipment? data? Have you gotten help or given help with computational analysis?  Have you shared protocols or methodologies?  Who have you worked on papers with, outside and inside your lab?

Let’s talk about it…Looking forward to seeing you there!

CRSB Hosts Social Hour with QB3 and Thermo Fisher Fall 2015

Our team had a chance to celebrate all of the good work, as part of the larger Quantitative Biosciences community – at the recent CRSB Hosted Social Hour, sponsored by Thermo Fisher and QB3.

See our Stellar Stand Outs, next to CRSB placard, who jumped in to help with storage, set up, and clean-up for the evening’s celebration.  A big thank you to —–

Anna McGeachy, Bo Li, Nick Bray, Mia Pulos, Luisa Arake de Tacca, James Lloyd, and Annsea Park from CRSB labs;


And thank you to – Jan Ambrosini (not pictured), (below) Dave Rogers, Eddie Cazarez, and Director, Susan Marqusee (see slide show) from QB3;

and the Thermo Fisher staff, Vinnie Shankar, and A.J. Nava. Thank you!


CRSB Pipeline to Graduate School: Ryan Muller & Hammond/Rio Labs

A little over two years ago I was accepted into Berkeley’s up-and-coming CRSB summer fellowship program. I showed up to the Rio and Hammond lab eager to learn and ready to research. I immersed myself in the science, made lifelong friends, and left with fond memories of my experiences. Now two years later, I am a first year MCB graduate student at Berkeley. Starting my first rotation once again in Don Rio’s lab, I have begun this time working on an applied project: enacting sequence-specific manipulation of alternative splicing. Through this work, we aim to generate a robust tool we can use to probe and understand the vast intricacies of RNA splicing. Although a challenging and somewhat risky project, I find myself excited every day to see the results of my experiments.

During my time at Berkeley, I have been able to interact with a wide array of talented scientists and I have become interested in RNA regulatory mechanisms that include RNA splicing, RNA degradation, and RNA translation control. As I embark on the daunting journey that is graduate school, I find myself thankful for the staff and scientists in the CRSB program that have supported me and mentored me from my naive undergraduate years to present day. Specifically, I would like to thank Don Rio, Ming Hammond, Jamie Cate, and Yeon Lee whose collective mentorship has left me excited to make my mark in science.







IGI Executive Director Jennifer Doudna and her research collaborator, Emmanuelle Charpentier, have been named 2015 Thomson Reuters Citation Laureates. Both are being acknowledged for their development of the CRISPR-Cas9 method of precision genome editing which enables researchers to identify potential treatments for genetic diseases.

This distinction is derived from an examination of the citation data within the Web of Science, highlighting the significance of research contributions in the eyes of the scientific community (based upon the number of times researchers cite published papers) and identifying the most influential researchers in chemistry, physics, physiology or medicine, and economics who are likely winners of the Nobel Prize now or in the future.

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